On the principle information, Spider-Man three brings again Alfred Molina’s Physician Octopus

Alfred Molina’s Otto Octavius, portrayed much more sympathetically than his comic book counterpart (at least at the time), was mentally connected to his robotic arms in Spider-Man 2 during a public demonstration with his fusion reactor that killed his wife Rosie. With the inhibitor chip protecting him from the weapons AI, Otto became unstable, and as Doctor Octopus, he stole money to rebuild his reactor and collided with Spider-Man in the process. In the end, however, Otto was able to take control of the weapons and sacrificed his life to prevent the nuclear reaction from destroying New York City.

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